Pregnancy Interaction

• Not safe to use during pregnancy.
• Can harm the fetus by interfering with the production of cholesterol needed for growth.
• Fenofibrate
• There isn't much safety data about pregnancy.
• Could be harmful to fetuses in animals.
• Don't do that unless you have to.
• In general
• Do not use Rosave F 10 if you are pregnant or breastfeeding.
• Women should use reliable birth control while taking this drug.

Faq For Medicine

Q1. What does Rosave F 10 do?

It lowers LDL cholesterol, total cholesterol, and triglycerides that are too high.

Q2. Is it safe for people with diabetes to use?

Yes, it is often used to treat diabetic dyslipidemia.

Q3. Is it possible for it to hurt your muscles?

Yes. When you take rosuvastatin and fenofibrate together, the chance of myopathy goes up.

Q4: Is it okay for me to drink alcohol?

Stay away from or cut back on alcohol; it puts more stress on the liver and raises triglyceride levels.

Q5. How long should I use this?

Usually for a long time, as your doctor says, along with diet and exercise.

Q6: Is it okay to take it at night?

Yes. Fenofibrate can be taken at any time, whereas rosuvastatin works best at night.

Q7. Is it okay to quit taking this medicine all at once?

No. Stopping suddenly could raise the risk of heart disease and high cholesterol.

Expert Advice

• Take at the same time every day, preferably at night.
• Eat less fat and live a heart-healthy life.
• If you have muscle discomfort, weakness, or black urine, you may have hurt your muscles.
• Don't drink grapefruit juice.
• Regular checks are needed:
• Tests for liver function (LFTs)
• Profile of lipids
• Tests for how well the kidneys work
• Tell the doctor before you have surgery.
• Don't mix with other fibrates unless your doctor tells you to.

 Side Effects

• Muscle ache or cramping
• Pain in the head
• Feeling sick
• Stomach problems
• Pain in the stomach
• Tiredness
• Not being able to go
• Very serious
• Myopathy / Rhabdomyolysis (serious muscle breakdown)
• Higher levels of liver enzymes
• Pancreatitis (linked to fenofibrate)
• Gallstones
• Problems with the kidneys
• Reactions to allergies
• Get help right away for:
• A lot of soreness in the muscles
• Eyes that turn yellow (jaundice)
• Stomach discomfort that won't go away
• Urine that is dark

How It Works

• A statin that stops the HMG-CoA reductase enzyme from working.
• Lowers LDL cholesterol, stops plaque from forming, and makes blood vessels healthier.
• Fenofibrate
• An activator of PPAR-alpha.
• It lowers triglycerides, raises HDL, and lowers fatty acids in the blood.
• Combined Effect
• Rosuvastatin decreases both total cholesterol and LDL cholesterol.
• Fenofibrate raises HDL and decreases triglycerides.
• They work together to fully regulate lipids in people with mixed dyslipidemia.

Medicine Interaction

• Fibrates (Gemfibrozil) -> high risk of serious muscle damage
• Blood thinners (Warfarin) → higher risk of bleeding
• Cyclosporine → harm to muscles and kidneys
• Anticoagulants: Keep a tight eye on INR
• Drinking alcohol raises the risk to the liver.
• Macrolide antibiotics → make statin toxicity worse
• Aluminum and magnesium antacids lower the amount of rosuvastatin that the body can take in.

 How to Use

• Take one tablet per day, ideally at night.
• Do not smash; just swallow with water.
• Can be taken after a meal to avoid stomach pain.
• If you skip a dose:
• Take it as soon as you remember.
• If the next dose is coming up soon, skip the one you missed.
• Don't take two doses

 Uses / indications

• Dyslipidemia mixed
• High levels of LDL cholesterol
• High triglycerides (Hypertriglyceridemia)
• Diabetics with several lipid problems
• Stop heart attacks and strokes caused by high cholesterol
• Lowering the risk of atherosclerotic cardiovascular disease