Pregnancy Interaction

• Not safe to use during pregnancy.
• Rosuvastatin could harm the fetus because cholesterol is necessary for fetal growth.
• There isn't enough safety data on fenofibrate to recommend usage during pregnancy, and it could be harmful to the fetus.
• Not suggested when breastfeeding because both parts may get into breast milk.
• Women who can get pregnant must use effective birth control while getting treatment.

Faq For Medicine

Q1. What does Jupiros-F Tablet do?
It is used for people who have high cholesterol and very high triglycerides and need more than one type of treatment.

Q 2. Is it okay to take it every day?
Yes, if your doctor tells you to. It is often necessary to use it regularly for a long time.

Q3. Is it okay to drink beer while taking this medicine?
Don't drink alcohol. It raises the chance of liver damage and muscle poisoning.

Q4. Does it hurt your muscles?
Yes. Rosuvastatin and Fenofibrate can both hurt muscles. If you have unexplained muscular soreness or black urine, tell your doctor.

Q5. When will cholesterol get better?
Cholesterol levels normally start to get better within two to four weeks of regular treatment.

Q6. What happens if I skip a dose?
If you remember, take it; if the next dose is coming up soon, skip it. Don't take twice as much.

Expert Advice

• Follow the directions properly; don't stop taking the tablet all of a sudden without talking to your doctor first.
• For the best outcomes, keep your weight in check, eat a low-fat diet, and exercise often.
• Tell your doctor right away if you have muscle pain, soreness, weakness, or yellowing of the skin or eyes.
• Regular monitoring is necessary:
• Tests for liver function
• Profiles of lipids
• Tests showing how well the kidneys work (Fenofibrate can impact the kidneys)
• Don't use with other cholesterol-lowering drugs unless your doctor says it's okay.
• Stay well-hydrated; dehydration makes muscle poisoning more likely.

Side Effects

• Common Side Effects
• Pain or spasms in the muscles
• Headache
• Feeling sick and throwing up
• Pain in the stomach, upset stomach
• Higher levels of liver enzymes
• Feeling weak or tired
• Serious Side Effects (Get medical help right away)
• Rhabdomyolysis (serious muscular disintegration)
• Hepatitis or liver harm
• Severe stomach pain (maybe pancreatitis)
• Allergic symptoms include a rash, swelling, and trouble breathing.

 How It Works

• Rosuvastatin
• It stops HMG-CoA reductase from working, which lowers cholesterol production.
• Lowers triglycerides, LDL, and VLDL; raises HDL.
• Fenofibrate
• PPAR-α receptors are activated, which speeds up the breakdown of triglycerides.
• Lessens the synthesis of VLDL and raises the levels of HDL.
• The Effect Together
• A big drop in triglycerides and a big drop in LDL means better control of mixed dyslipidemia.

Medicine Interaction

• Big Interactions
• With cholesterol medications:
• Gemfibrozil and other fibrates have a very significant risk of muscle toxicity.
• High doses of statins increase the risk of muscle damage.
• With blood thinners:
• Warfarin → Fenofibrate makes the blood thinner effect stronger, which raises the risk of bleeding.
• With immunosuppressants:
• Cyclosporine → Fenofibrate causes severe renal damage.
• With Alcohol:
• Makes it more likely that your liver will be damaged and your muscles will break down.
• Other things that happen:
• Antacids → Lower the amount of rosuvastatin that is absorbed (wait 2 hours).
• Diabetes drugs may have a small effect on blood sugar levels.

 How to Use

• Usually taken once a day or as advised by the doctor.
• Do not crush or chew. Just swallow with water.
• Can be taken with food to help with gastrointestinal problems.
• Keep the same schedule every day.
• If you forget a dose, take it as soon as you remember unless the next dose is coming up quickly.

Uses / indications

• Mixed dyslipidemia is when you have high cholesterol and high triglycerides at the same time.
• Hypertriglyceridemia not managed with statin monotherapy
• Preventing heart disease in people who are at high risk
• Lowering LDL, VLDL, and triglycerides while raising HDL