Pregnancy Interaction

• Not safe at all during pregnancy.
• Letrozole is a drug that stops estrogen from working. It can hurt the fetus, cause a miscarriage, or cause birth problems.
• This medicine should not be taken by women who are pregnant, planning to becoming pregnant, or breastfeeding.
• If you get pregnant while getting treatment, stop right once and see a doctor.

Faq For Medicine

Q1.What is Letro Plus 2.5 mg for?

It is used to treat breast cancer in women who have already gone through menopause and to help some women get pregnant by making them ovulate.

Q2. Does Letrozole help you get pregnant?

Yes, doctors commonly give it to women who can't become pregnant (such those with PCOS) to help them ovulate.

Q3. How long after taking Letrozole will ovulation happen?

Usually 5 to 10 days after finishing the course.

Q4. Is it safe for women who haven't gone through menopause to use Letrozole?

Only under close medical supervision (typically for infertility therapy).

Q5. How long does it take for Letrozole to work on breast cancer?

It can take weeks or months to see a full reaction.

Expert Advice

• Don't use if pregnant or breastfeeding.
• Stay away from alcohol; it could make you feel more tired or dizzy.
• It is suggested that bone density, cholesterol levels, and liver function be checked on a regular basis (long-term use).
• Helps women with PCOS by making them ovulate; must be taken exactly as directed.
• Tell your doctor if you have vaginal bleeding, very bad hot flashes, or bone discomfort.
• Make sure you get enough calcium and vitamin D.

Side Effects

• Often:
• Flashes of heat
• Pain in the head
• Dizzy
• Tiredness
• Feeling sick
• Pain in the joints or bones
• Sweating
• Dryness in the vagina
• Very serious:
• Osteoporosis (thinning of bones)
• Too much cholesterol
• Very bad allergic reactions
• Vision that is not clear
• Legs that are swollen (a potential clot)
• If you have severe symptoms, get medical help right away.

 How it works

• Letrozole stops aromatase from working.
• It stops the enzyme aromatase from working, which lowers the amount of estrogen made by the body.
• In breast cancer, lower levels of estrogen slow down or stop the proliferation of cancer cells.
• In infertility, lower estrogen levels lead to higher levels of FSH (Follicle-Stimulating Hormone), which triggers ovulation.

Medicine Interaction

• Be careful when using with:
• Medicines that contain estrogen (oppose effect)
• Tamoxifen
• Warfarin is a blood thinner.
• Medicines for the heart
• Drugs that reduce cholesterol
• Medicines for seizures (such phenytoin and carbamazepine)
• Alcohol (makes you feel dizzy)
• Always tell the doctor about any other medications you are taking.

 How to Use

• To cure infertility:
• Most of the time, you take it once a day for five days, usually from Day 2 to Day 6 or Day 3 to Day 7 of your menstrual cycle.
• The dose and schedule depend on what the doctor says.
• For breast cancer:
• Usually taken once a day, at the same time every day.
• You can take it with or without food.
• Don't quit treatment without talking to your doctor first.
• In general:
• Do not crumble or chew; just swallow whole with water.
• If you forget a dose, take it as soon as you remember, unless it's almost time for the next one.

 Uses / indications

• Letro Plus 2.5 mg Tablet is used for:
• Hormone receptor-positive breast cancer in women who have gone through menopause
• Treatment for infertility (inducing ovulation in women with anovulation/PCOS)
• Advanced or metastatic breast cancer
• Adjuvant treatment for breast cancer in its early stages