Uses / Indications:
Inducing ovulation in women experiencing infertility due to PCOS
Infertility without a known cause
Stimulating ovulation in assisted reproductive technologies (ART)
Occasionally utilized off-label for infertility associated with endometriosis.
Pregnancy interaction:
Letrozole is not safe to use when pregnant.
It is only used before conception to make ovulation happen.
If you get pregnant, you need to stop taking the drug right away.
Animal studies show that it could harm the fetus, hence it should not be taken after pregnancy.
Expert advice:
You should only take this medicine with the help of a doctor.
Follow the instructions and start therapy on the second, third, or fifth day of your period.
Ultrasound may be used by your doctor to keep an eye on the growth of ovarian follicles.
Tell your doctor if you have liver disease, ovarian cysts (not PCOS-related), or bleeding from your uterus that isn't typical.
To boost your chances of getting pregnant, keep your weight in check, eat a balanced diet, and make changes to your lifestyle.
Side Effects:
Flashes of heat
Pain in the head
Tiredness or dizziness
Pain in the joints or muscles
Feeling sick
Very serious (rare):
Vision that is blurry
A lot of bleeding from the vagina
Severe abdominal ache (potential ovarian hyperstimulation)
Allergic symptoms include a rash, swelling, and trouble breathing.
How to use:
Take one tablet every day for five days in a row, starting when your doctor tells you to.
Take it all at once with water, with or without food.
Don't skip dosages.
Use ultrasound or ovulation kits to keep track of when you ovulate.
Don't take medicine on your own and don't go beyond the suggested cycles.
How it works:
Letrozole is an aromatase inhibitor that stops the body from making estrogen.
When estrogen levels drop, the pituitary gland releases more FSH (follicle-stimulating hormone).
This makes the ovaries grow and release mature eggs, which makes it more likely that you will get pregnant.
Faq for medicine:
Clomipure-L 2.5mg Tablet: Frequently Asked Questions
Q1. Is it OK for me to use Clomipure-L if I am already pregnant?
No. It shouldn't be used when you're pregnant.
Q2. How long does it take to make ovulation happen?
Ovulation normally happens 5 to 10 days after the course is over.
Q3. What is Clomipure-L different from Clomiphene?
Clomiphene stops estrogen from working, while Letrozole lowers the amount of estrogen made. Letrozole works better for a lot of women, especially those with PCOS.
Q4: How many times may I take Clomipure-L?
Most of the time, doctors suggest 5 to 6 cycles, depending on how well the patient responds.
Q5. Will taking Clomipure-L make it more likely that I will have more than one baby?
The risk is lower than with Clomiphene, although twins or more may still happen.
Medicine interaction:
Medications that contain estrogen, such as HRT or birth control pills, Make it less effective.
Tamoxifen or other hormone treatments → could change how the medicine works.
Some medicines that make liver enzymes work better (such phenytoin, carbamazepine, and rifampicin) may lower Letrozole levels.
