Pregnancy Interaction

• Not safe for pregnant women.
• Women who are pregnant should not take letrozole since it can hurt the fetus.
• Women who can get pregnant must use effective birth control while taking it, except during cycles of fertility treatment.
• If you get pregnant while getting treatment, stop right once and see a doctor.
• Not a good idea while breastfeeding.

Faq For Medicine

Q1. What is Letpro 2.5 mg for?
Main use: Hormone-positive breast cancer in women who have gone through menopause.
Secondary use: Induction of ovulation in cases of infertility (off-label).

Q2. Can Letrozole help you get pregnant?
Yes. Many women with PCOS or unexplained infertility use it to help them ovulate.

Q 3. How long does it take to get to work?
For breast cancer, it operates slowly over the course of weeks to months.
For ovulation induction: ovulation normally happens 5 to 10 days following the last pill.

Q4. Is it safe for ladies who haven't gone through menopause yet?
Not usually, unless a gynecologist is watching for fertility treatment.

Q5. Is it a hormone?
No. It is an aromatase inhibitor that lowers the amount of estrogen in the body.

Q6. Can it make you lose your pregnancy early?
It shouldn't be used after ovulation unless a doctor says so, because it could impair the early stages of pregnancy.

Expert Advice

• If you are pregnant, breastfeeding, or wanting to get pregnant, don't take this.
• During fertility treatment:
• Take exactly as directed, which is usually on days 2–5 of your cycle.
• Use scans or ovulation kits to keep an eye on ovulation.
• Regular:
• Tests for liver function
• Tests for bone density (risk of osteoporosis)
• Make sure you get enough calcium and vitamin D.
• To lower your chances of osteoporosis, don't smoke or drink alcohol.
• Tell your doctor if you have symptoms like severe bone pain, heat flashes, or trouble breathing.

Side Effects

• A lot:
• Flashes of heat
• Tiredness
• Pain in the head
• Feeling dizzy
• Feeling sick
• Pain in the joints or muscles
• Not as common:
• Thinning hair
• Gaining weight
• Not being able to sleep
• Legs getting bigger
• Very serious (rare):
• Osteoporosis and broken bones
• A very bad allergic reaction
• Clots in the blood
• Breathlessness
• Problems with the liver
• Get medical help right away if you have a bad response.

 How It Works

• Letrozole stops aromatase from working.
• It stops the aromatase enzyme from making estrogen in the body.
• Effects:
• In the case of breast cancer:
• Less estrogen reduces or stops the growth of cancers that need estrogen to grow.
• In the process of ovulation induction:
• Low estrogen stimulates the pituitary gland, which releases more FSH, which causes ovulation.

Medicine Interaction

• Be careful when using with:
• Hormonal Drugs
• Hormone treatments with estrogen
• Pills for birth control
• (Both can make letrozole work less well.)
• Other Interactions
• Tamoxifen (may lessen impact)
• Steroids (keep an eye on bone health)
• Blood thinners (keep an eye on them if you need to)
• Alcohol (may make dizziness and bone loss worse)
• No big problems with food.

 How to Use

• For Breast Cancer
• Usually, you take one tablet at the same time every day.
• You can take it with or without food.
• Therapy for a long time, usually five years or more.
• To Start Ovulation
• Usually used once a day for five days, starting on days 2–5 of the menstrual cycle.
• Follow your gynecologist's directions exactly.
• Instructions in General
• Drink water and swallow entire.
• If you miss a dose, don't take two; just take the following one as usual.
• Keep doing regular follow-up tests.

 Uses / indications

• 1. Breast Cancer (Primary Indication)
• Hormone receptor-positive breast cancer in women who have gone through menopause
• Early-stage cancer (adjuvant treatment)
• Breast cancer that has spread
• Stopping the disease from coming back
• 2. Induction of Ovulation (Off-Label Use)
• Women who have PCOS
• Infertility without a known cause
• Women who don't ovulate frequently
• To increase the likelihood of pregnancy during IUI or scheduled intercourse