Uses / Indications 

• Type 2 Diabetes Mellitus - To keep blood sugar levels from getting too high
• Combination therapy is used when one antidiabetic drug isn't enough.
• Post-Meal Blood Sugar Control: This helps keep blood sugar levels from going up too high after meals.
• Used with diet and exercise as an addition to lifestyle changes
• Prevention of Diabetes Complications—helps lower the risk of damage to the kidneys, nerves, and eyes.

 How It Works

• Tenali M 500 is made up of two diabetes medicines:
• 500 mg of Metformin
• Lowers the amount of glucose produced in the liver
• Makes insulin more effective
• Lessens the amount of glucose that the intestines take in.
• Teneligliptin (20 mg)
• Stops the DPP-4 enzyme from working
• Raises levels of incretin hormones
• Increases the release of insulin after meals and lowers glucagon.
• When used together, they help control blood sugar levels better and lower the risk of hypoglycemia.

 How to Use

• Take the medication exactly as your doctor told you to.
• Usually taken with meals once or twice a day
• Take the tablet with water and swallow it whole.
• Don't chew or crush.
• Take at the same time every day.
• Check your blood sugar levels often.

Pregnancy Interaction

• Not usually recommended during pregnancy
• There isn't a lot of information about how safe teneligliptin is during pregnancy.
• Insulin is usually the best choice during pregnancy.
• Only use if your doctor thinks the benefits are greater than the risks.
• You should only breastfeed if your doctor says it's okay.

 Side Effects 

• Feeling sick
• Stomach problems or diarrhea
• Feeling bloated or pain in the stomach
• Pain in the head
• Side Effects That Are Rare or Serious:
• Low blood sugar (more common if used with insulin or sulfonylureas)
• Lactic acidosis (extremely rare, because of metformin)
• Reactions to allergies (rash, itching, edema)
• Pain in the joints (rare)
• If you feel really weak, breathe quickly, throw up a lot, or are unusually weary, you should see a doctor.

Medicine Interaction

• Tenali M 500 may have effects on:
• Insulin or sulfonylureas – higher chance of having low blood sugar
• Alcohol raises the risk of lactic acidosis.
• Contrast dyes (used in scans) can change how the kidneys work.
• Some heart and kidney drugs, such cimetidine, may change the levels of metformin.
• CYP3A4 inhibitors may change the levels of teneligliptin.
• Always tell your doctor about any supplements or medicines you take.

Expert Advice

• To lessen stomach adverse effects, take the tablet with food.
• Eat a balanced diet and work out often if you have diabetes.
• Check your blood sugar and kidney function on a regular basis.
• Don't drink too much alcohol.
• Tell your doctor if you have any of these symptoms of low blood sugar: sweating, shaking, or feeling dizzy.
• Don't stop taking the medicine without talking to your doctor first.

Faq For Medicine

Q1: Is it okay to take Tenali M 500 with food?
Yes, you should take it with food.

Q2. Does it make blood sugar levels low?
Taking it alone has a modest risk, but taking it with insulin or sulfonylureas raises the risk.

Q3. Is it safe to use for a long time?
Yes, it is safe to use for a long time under the care of a doctor.

Q4. Can I consume alcohol while taking it?
Don't drink too much alcohol because it can make adverse effects worse and cause blood sugar levels to change.

Q5: What happens if I forget a dose?
As soon as you recall, take it. If it's close to the next dose, don't take the missing one. Don't take twice as much.