Uses / Indications:
Piolet 15mg Tablet is used in the treatment of type 2 diabetes. It is used in addition to diet and exercise to improve blood sugar control in adults with type 2 diabetes.
Interactions / Warnings:
NA
Pregnancy interaction:
Piolet 15mg Tablet may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Expert advice:
Piolet helps to control blood sugar level and avoids long-term complications. You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Piolet. Full effect may be visible after several weeks of starting Piolet. Weight gain, headache, and swelling due to fluid build-up may occur. Notify your doctor if you experience shortness of breath, heart problems, or any abnormal swelling. May not be suitable for patients with a history of heart failure or bladder cancer.
Side Effects:
Weight gain, Blurred vision, Respiratory tract infection, Numbness, Bone fracture.
How to use:
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Piolet 15mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How it works:
Piolet 15mg Tablet is an anti-diabetic medication. It works by increasing the body's sensitivity to insulin, a natural substance that helps control blood sugar levels.
Faq for medicine:
Is Piolet a blood thinner? : No. Piolet is an anti-diabetic medication. Blood thinners are the medicine that prevents the formation of a harmful blood clot. These include medicines like Aspirin, Heparin and Warfarin.|Is Piolet a diuretic? : No. Piolet is not a diuretic. It is used in the treatment of Diabetes Mellitus. Diuretics are those medicine which increases urination.|Can Piolet used in Hepatitis B infection? : Some studies have shown that Piolet may be helpful in preventing Hepatitis B Virus-associated Hepatocellular Cancer (Liver Cancer). However, these findings are still very preliminary and clear role has not been established.|Can Piolet used in Hepatitis C infection? : Piolet has been shown to inhibit Liver Cancer (HCC) recurrence in overweight Hepatitis C Virus-infected diabetic patients. It also improved insulin resistance (a state where the body is resistant to the effects and functions of the insulin hormone) in them.|Can Piolet used along with Vitamin D? : Studies indicate that Vitamin-D combined with Piolet may be more effective in improving Bone Mineral Density and Bone Metabolism than Vitamin-D or Piolet alone in the treatment of Diabetes Mellitus patients with kidney dysfunction (Diabetic Nephropathy).|Can Piolet be used along with sitagliptin? : Combination therapy with Sitagliptin and Piolet leads to a substantial and sustained improvement in glycemic (blood sugar) control compared to the treatment with Piolet alone. This is useful for patients who cannot tolerate Metformin or Sulfonylureas.|Is there any role of Piolet in Alzheimer disease? : Recent evidence suggests that Piolet may be beneficial in Alzheimer's disease (AD), decreasing the cognitive decline early in the disease process. However, larger studies are now in progress to establish the same.|Can Piolet and repaglinide combined in diabetes treatment? : For patients who previously failed oral antidiabetic therapy, the combination of Repaglinide and Piolet have acceptable safety, with greater reductions of glycemic parameters (blood sugar levels) than using either agent alone.|Does Piolet cause urinary bladder tumour? : Large population studies indicate that Piolet is associated with an increased risk of bladder cancer. The absence of an association of bladder cancer with the other drug of the same class, Rosiglitazone, suggests that the increased risk is drug specific and not a class effect.|Can Piolet be used along with glimepiride in diabetes? : Piolet when added to Glimepiride in Patients with Diabetes Mellitus, has been found to significantly reduce plasma lipid levels and significant improvement in blood pressure control related to a reduction in the insulin resistance.|Is Piolet a steroid? : No. Piolet is not a steroid. It is an anti-diabetic medication which belongs to the class of thiazolidinediones.|How to use Piolet? : Piolet is an anti-diabetes drug used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes. Piolet acts as an insulin sensitizer and decreases the extent of insulin resistance in the body too.|How safe is Piolet? : Piolet cardiovascular safety profile compares favourably with that of Rosiglitazone. Piolet has been found to be associated with bladder tumours but causality assessment has not been proved yet.|How does Piolet cause oedema? : Piolet increases the permeability of fluid in tiny blood vessels called capillaries. This results in easier movement of fluids across the membrane and their consequent accumulation, resulting in oedema (puffiness). Also, Piolet causes increased sodium and water reabsorption from the kidney that contributes to the oedema.|How does Piolet cause bladder cancer? : The mechanism behind the link between Piolet use and bladder cancer is still unknown. Studies have suggested that use of Piolet for more than one year results in increased risk of development of tumour of the urinary bladder.|How Piolet protects against atherosclerosis? : Studies in animals have concluded that Piolet improves the elasticity of the aortic wall ( the aorta is a large blood vessel that arises from the heart and supplies oxygenated blood to the rest of the body). This may be a mechanism by which it protects against atherosclerosis, but more studies are needed to confirm this.|Can Piolet be used with insulin? : The addition of Piolet reduces daily insulin dosages, but study findings have not been consistent. Improvement of lipid profiles has also been weak with this combination therapy. Long-term studies are needed before any conclusions can be reached. Combination therapy should be primarily used for patients who achieve an insufficient reduction in blood sugar with insulin alone.|Can Piolet used for dementia? : Findings indicate that Piolet treatment is associated with a reduced dementia risk in Diabetes mellitus patients. Prospective studies are needed to evaluate a possible neuroprotective effect in these patients in an ageing population.|Can Piolet used for infertility? : Piolet may be of use in infertile patients with polycystic ovary syndrome (PCOS) who are resistant to conventional ovulation induction such as by drugs like Clomiphene, Dexamethasone, or Metformin.|Can Piolet used for psoriasis? : The use of Piolet for plaque psoriasis treatment is controversial. Some studies revealed no effect of Piolet 30 mg daily neither on the clinical response of moderate-to-severe psoriasis whereas others demonstrate that it could be considered as an efficacious and safe agent for the treatment of plaque psoriasis.|Can Piolet used for autism? : In a research study in a small number of autistic children, daily treatment with 30 or 60 mg Piolet for 3–4 months induced apparent clinical improvement. Piolet should be considered for further testing of therapeutic potential in autistic patients but as of now, autism is not an approved indication for Piolet use.|Can Piolet be used in depression? : Piolet, either alone or as add-on therapy to conventional treatments, could clinically benefit patients of major depression according to a study.|Can Piolet used for weight loss? : A recent study shows that although Piolet causes a significant decrease in blood sugar, HbA1C and lipid levels, it is associated with weight gain, which would limit its utility. It has not been shown to cause weight loss.|Can Piolet be used to treat fatty liver? : Piolet has also been used to treat non-alcoholic steatohepatitis (fatty liver), but this use is presently considered experimental.|Can Piolet be used for secondary stroke prevention? : Piolet reduces recurrent stroke and major vascular events in stroke patients with insulin resistance, prediabetes, and diabetes mellitus. However, its use as a preventive therapy requires more research.
Medicine interaction:
Piolet with Trimethoprim|Piolet with Lactase|Piolet with Fluoxetine|Piolet with Gemfibrozil|Piolet with Hydrocortisone|Piolet with Dexamethasone|Piolet with Glucosamine|Piolet with Dapoxetine|Piolet with Nicotinic acid / Niacin|Piolet with Triamcinolone|Piolet with Chlorthalidone|Piolet with Deflazacort|Piolet with Fenofibrate|Piolet with Triamterene|Piolet with Propranolol|Piolet with Insulin Glulisine|Piolet with Escitalopram|Piolet with Metolazone|Piolet with Rasagiline|Piolet with Budesonide|Piolet with Pancreatin|Piolet with Methylprednisolone|Piolet with Diacerein|Piolet with Citalopram|Piolet with Pindolol|Piolet with Octreotide acetate|Piolet with Orlistat|Piolet with Insulin Lispro|Piolet with Clonidine|Piolet with Spironolactone|Piolet with Betamethasone|Piolet with Paroxetine
