Pregnancy Interaction

• Not advised during pregnancy.
• Combination antidiabetic medication could have an effect on the development of the fetus.
• If you are pregnant or trying to get pregnant, you should tell your doctor right away so they can suggest a different treatment.
• Not suggested for breastfeeding because some parts may get into the milk.

 Uses / Indications 

• Treatment for type 2 diabetic mellitus
• Used when single or dual therapy doesn't do a good job of controlling blood sugar
• Regulates blood glucose levels during fasting and after meals.
• Makes insulin more sensitive and helps it work better.
• Helps stop diabetes from causing problems with the kidneys, nerves, eyes, and heart in the long run.

How It Works

• Pioglitazone makes muscle and fat cells more sensitive to insulin.
• Glimepiride: Makes the pancreas make more insulin.
• Metformin lowers the amount of glucose made by the liver and makes insulin work better.
• The combination works in several ways to keep blood sugar levels stable and low.

How to Use

• Take precisely what your doctor tells you to.
• Usually taken once a day with food to help with gastrointestinal problems and low blood sugar.
• Do not crush or chew the tablet; just swallow it whole with water.
• Take it every day at the same time.
• While using this drug, don't miss meals.

Side Effects

• Low blood sugar (hypoglycemia)
• Gain weight
• Feeling sick, having diarrhea, or having stomach pain
• Pain in the head
• Feet or ankles that are swollen
• Side Effects That Are Rare but Serious:
• Very low blood sugar
• Heart failure or fluid retention
• Problems with how the liver works
• Lactic acidosis (extremely rare, linked to metformin)
• If you feel dizzy, confused, out of breath, or very weak, get medical care right away.

Medicine Interaction

• Insulin and other medications for diabetes
• Alcohol (raises the chance of hypoglycemia and lactic acidosis)
• Medicines for high blood pressure
• Rifampicin (lessens the action of pioglitazone)
• Iodinated contrast agents are utilized in imaging tests.
• ➡️ Always tell your doctor about any vitamins, minerals, or other supplements you are taking.

Expert Advice

• Check your blood sugar levels often.
• Eat a balanced diet for diabetics and work out on a regular basis.
• Don't drink alcohol.
• It is a good idea to check your kidneys, liver, and heart on a regular basis.
• If you have hypoglycemia, keep some fast-acting sugar on hand.
• Tell your doctor if you have heart disease, liver problems, or low blood sugar episodes that happen often.

Faq For Medicine

Q1. Can K-Pio-GM 2 Tablet lower blood sugar?
Yes. Glimepiride might cause low blood sugar, especially if you don't eat.

Q2. What is the difference between GM 1 and GM 2?
GM 2 usually has a larger dose of glimepiride, which makes it better in lowering blood sugar.

Q3. Is it safe to take this medicine for a long time?
Yes, but only when a doctor is watching and checking on them often.

Q4. Is this medicine safe for older people to take?
Yes, however they need to be watched more closely for low blood sugar.

Q5. Is it safe to take K-Pio-GM 2 when pregnant?
No, you should stay away from it.