Uses / Indications:
Fever (any cause, including infections, post-vaccination)
Mild to moderate pain
Toothache, teething pain
Ear pain (otitis media)
Headache
Sore throat pain
Post-surgical pain
Inflammatory conditions
Sprains, strains, minor injuries
Juvenile idiopathic arthritis (chronic use under supervision)
Pregnancy interaction:
First Trimester (0–12 weeks):
Use only if clearly needed. Some studies suggest a possible risk of miscarriage or congenital malformations (e.g., heart defects) when used in early pregnancy.
Second Trimester (13–28 weeks):
May be used with caution and medical supervision. Short-term, low-dose use is sometimes considered safe, but prolonged use should be avoided.
Third Trimester (29 weeks–delivery):
Contraindicated due to risks of:
Premature closure of ductus arteriosus (fetal heart circulation problem)
Pulmonary hypertension in newborn
Reduced amniotic fluid (oligohydramnios)
Delayed or prolonged labor
Increased maternal and neonatal bleeding risk
Safer alternative in pregnancy: Paracetamol (acetaminophen) is generally the first-line choice.
Expert advice:
Use the lowest effective dose for the shortest possible duration.
Always check the child’s weight to calculate the correct dose.
Do not give with other NSAIDs (e.g., aspirin, diclofenac).
If fever lasts >3 days or pain persists >5 days, seek medical advice.
Monitor for allergic reactions (skin rash, breathing difficulty).
Store the syrup at room temperature, away from direct sunlight.
Discard the bottle within 6 months of opening or as per label.
Side Effects:
Common:
Upset stomach, nausea, vomiting
Indigestion, heartburn
Mild diarrhea or constipation
Headache, dizziness
Less Common but Serious:
GI bleeding (vomit with blood, black stools)
Allergic reactions: rash, swelling of face/lips/tongue, difficulty breathing
Kidney problems (reduced urine, swelling in legs)
Severe skin reactions (rare but serious, e.g., Stevens-Johnson Syndrome)
How to use:
Shake bottle well before each use.
Measure dose with provided syringe/cup (never use household spoons).
Give with or after meals.
Dosing is weight-based (typically 5–10 mg/kg every 6–8 hours).
Do not exceed 40 mg/kg/day or maximum prescribed by doctor.
If dose is missed → give as soon as possible, but skip if next dose is near. Never double dose.
How it works:
FEBRILIX 100MG/5ML SYRUP is an NSAID (Non-Steroidal Anti-Inflammatory Drug).
It works by inhibiting Cyclo-oxygenase (COX-1 and COX-2) enzymes.
This blocks production of Prostaglandins, the chemicals responsible for:
Fever (resetting brain temperature center)
Pain (sensitizing nerves)
Inflammation (swelling, redness)
Faq for medicine:
Q1. Can I give FEBRILIX 100MG/5ML SYRUP to my baby under 6 months?
No, it is generally not recommended for infants below 6 months unless prescribed by a pediatrician.
Q2. Is FEBRILIX 100MG/5ML SYRUP stronger than Paracetamol for fever?
Yes, Ibuprofen may provide longer-lasting relief (up to 6–8 hours) and has anti-inflammatory action, unlike paracetamol.
Q3. Can FEBRILIX 100MG/5ML SYRUP cause sleepiness?
Not usually. If drowsiness occurs, consult a doctor.
Q4. Can I give FEBRILIX 100MG/5ML SYRUP on an empty stomach?
It can irritate the stomach, so best given after food or milk.
Q5. How often can I give FEBRILIX 100MG/5ML SYRUP to my child?
Usually every 6–8 hours, but do not exceed 3–4 doses in 24 hours.
Q6. Can FEBRILIX 100MG/5ML SYRUP affect the kidneys?
Yes, prolonged use or overdose may harm kidneys, especially in dehydrated children. Always ensure adequate fluid intake.
Q7. Is FEBRILIX 100MG/5ML SYRUP safe for children with asthma?
Not always – in some children, Ibuprofen may worsen asthma symptoms. Consult a doctor first.
Medicine interaction:
Avoid combining with:
Other NSAIDs / Aspirin → increases stomach bleeding risk.
Blood thinners (Warfarin, Heparin, Apixaban, etc.) → high bleeding risk.
Corticosteroids (Prednisolone, Dexamethasone) → GI ulcer risk.
Methotrexate → Ibuprofen reduces clearance → toxicity risk.
Lithium → increases lithium levels → toxicity.
Antihypertensives (ACE inhibitors, ARBs, Diuretics) → reduced kidney function.
Alcohol → higher risk of gastric irritation and bleeding.
