Pregnancy Interaction

• Not safe to use during pregnancy, especially in the second and third trimesters.
• Telmisartan can induce prenatal renal failure, low amniotic fluid, growth restriction, cranial and developmental malformations, and even fetal mortality (though this is rare).
• Amlodipine is not very risky, but it is not suggested unless it is needed.
• If you get pregnant, stop right away and see a doctor.
• Not a good idea while breastfeeding.

 FAQ for Medicine

Q1: What is the Amlosafe-TM 80/5 Tablet used for?
For high blood pressure when taking lesser doses or just one medicine isn't enough.

Q2: How long does it take to work?
Effect starts in 1–2 hours.
Maximum control: 2–4 weeks

Q3. Does it make things swell?
Yes, Amlodipine can make your ankles and feet swell.

Q4: Can I eat it?
Yes, you can take it with or without food.

Q5. Is it safe for people with kidney problems?
Telmisartan protects the kidneys, however potassium and creatinine levels need to be checked.

Q6. Is it safe to drive after taking the medicine?
If you feel dizzy or tired, especially at first, don't drive.

Q7: Is it okay to discontinue taking the medication once my blood pressure is normal?
No. Stopping suddenly could make BP worse.

Expert Advice

• Don't use during pregnancy; use effective birth control.
• Check your blood pressure on a regular basis.
• Don't use potassium salt replacements unless your doctor tells you to.
• A low-salt diet and raising your legs can help with swelling caused by amlodipine.
• Tell your doctor about any symptoms you have, such as:
• Keep making adjustments to your life:
• – Don't smoke or drink alcohol; – Eat a low-sodium diet; – Work out regularly; – Control your weight;

 Side Effects

• Feeling dizzy
• Pain in the head
• Swelling in the feet and ankles
• Tiredness
• Low blood pressure
• Cramps in the muscles
• Not as Common:
• Heart palpitations
• Flushing
• Pain in the stomach
• Pain in the back
• Serious (rare):
• Very low blood pressure makes you faint.
• Decline in kidney function
• Very bad allergic reaction
• If you get severe dizziness, face swelling, or trouble breathing, get medical help right once.

 How It Works 

• It stops angiotensin-II receptors from working, which relaxes blood vessels.
• Lowers blood pressure and protects the heart and kidneys.
• More powerful than a 40 mg dose.
• CCB Amlodipine:
• Lowers blood flow by relaxing the muscles in the arteries.
• Lowers the amount of effort the heart has to do.
• Stops angina attacks.
• Combined effect: ✔ Strong BP decrease ✔ Dual-mechanism control ✔ Protects heart and kidneys ✔ Ideal for those needing higher potency BP therapy

Medicine Interaction

• Be careful when using with:
• ➤ Potassium supplements or diuretics that don't lose potassium
• Risk of too much potassium (hyperkalemia).
• ➤ NSAIDs (Ibuprofen, Diclofenac)
• Lower BP and put stress on the kidneys.
• ➤ Other drugs that lower blood pressure
• Could make blood pressure drop too low.
• ➤ Lithium
• Raises the chance of lithium poisoning.
• ➤ Antifungals and macrolide antibiotics
• Raise the levels of Amlodipine.
• ➤ Booze
• Makes you feel dizzy and faint.

 How to Use

• Take once a day at the same time.
• Can be taken with or without food.
• Take the tablet whole with water.
• If you miss a dosage, take it as soon as you remember. If the following dose is near, skip it. Do not take two doses.
• Keep up with therapy even if your blood pressure is normal.

 Uses / Indications

• High blood pressure (hypertension)
• BP not managed with reduced dosages or monotherapy.
• Patients needing strong dual-mechanism Control of blood pressure
• To lower the chance of: – having a heart attack – having a stroke
• - damage to the kidneys (particularly in people with diabetes)