Pregnancy Interaction

• Not safe for pregnant women, especially in the second and third trimesters.
• Telmisartan may result in: – fetal renal impairment – diminished amniotic fluid – growth retardation – cranial anomalies – fetal demise (infrequent)
• Hydrochlorothiazide may slow down blood flow to the placenta and throw off the balance of electrolytes.
• Amlodipine is safer than other drugs, but you shouldn't take it without a doctor's supervision.
• If you get pregnant, stop right away and call your doctor.
• Not a good idea while breastfeeding.

Faq For Medicine

Q1: What is the purpose of Amlosafe 3D Tablet?
It is used to lower blood pressure, especially when one or two BP drugs don't work.

Q2: Can I eat it?
Yes, you can take it with or without food.

Q3. Does it make things swell?
Some people who take amlodipine may notice edema in their ankles or feet.

Q4. How long does it take to start working?
First effect: 1 to 2 hours
Full regulation of blood pressure: 2–4 weeks

Q5. Can I stop taking the medication when my blood pressure goes back to normal?
No. Stopping suddenly could make your blood pressure go up quickly.

Q6. Does it make you pee more?
Yes, because of Hydrochlorothiazide.

Q7. Is it safe for people with kidney problems?
Be careful when using. It is necessary to keep an eye on renal function and electrolytes.

Expert Advice

• Don't use during pregnancy; use a dependable form of birth control.
• Check your blood pressure often.
• Drink more fluids unless your doctor tells you not to.
• Raising your legs can help minimize swelling caused by amlodipine.
• Stay away from foods heavy in salt and salt substitutes that have potassium in them.
• Tests in the lab that need to be done every so often:
• – potassium
• – salt – how well the kidneys work
• Tell your doctor if you have any of these symptoms: severe dizziness, swelling in your legs, muscle cramps, heart palpitations, or not urinating as often as usual.

 Side Effects 

• Feeling dizzy
• Pain in the head
• Swelling in the feet and ankles
• More frequent urination
• Tiredness
• Cramps in the muscles
• Low levels of potassium
• Not as Common:
• Flushing
• Feeling sick
• Weakness
• Problems with sleep
• Very serious (rare):
• Very low blood pressure
• Very bad imbalance of electrolytes
• Decline in kidney function
• Allergic response (swelling of the face and lips)
• If you get severe shortness of breath, fainting, or swelling in your face, get medical help right once.

 How It Works

• 1. Telmisartan (ARB)
• Blocks angiotensin-II receptors, which makes blood arteries relax and lowers blood pressure.
• Keeps the heart and kidneys safe.
• 2. Amlodipine (CCB)
• It relaxes the muscles in the arteries, which makes blood flow better.
• Lessens stress on the heart.
• 3. Hydrochlorothiazide (a diuretic)
• Eliminates surplus sodium and water, hence reducing blood volume.
• Boosts the blood pressure-lowering effects of Telmisartan and Amlodipine.
• Combined effect: ✔ Strong BP lowering ✔ Long-lasting control ✔ Useful in resistant or uncontrolled hypertension

Medicine Interaction

• Be careful with:
• ➤ Potassium supplements or potassium-sparing diuretics
• Telmisartan may produce excessive potassium levels.
• ➤ Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and diclofenac
• Lower blood pressure management and hurt the kidneys.
• ➤ Medicines that fight diabetes
• HCTZ might change how well glucose is controlled.
• ➤ Lithium
• The risk of lithium poisoning goes up.
• ➤ Other drugs for high blood pressure
• Risk of very low blood pressure.
• ➤ Alcohol
• Makes dizziness and low blood pressure worse.

 How to Use

• Take once a day, or as directed.
• Take it every day at the same time.
• You can take it with or without food.
• Take it all at once with water.
• If you miss a dosage, do the following: – Take it when you remember; – Skip it if the next dose is close; – DO NOT increase the dose.

 Uses / Indications

• High blood pressure (hypertension)
• BP not managed with monotherapy or combination therapy
• Patients that need three mechanisms Control of blood pressure
• Lowering the risk of stroke, heart attack, and kidney damage in those with high blood pressure