Pregnancy Interaction

• When a doctor prescribes it, it is usually safe (Category B).
• There is no proof that it hurts the fetus, but it should only be used if it is absolutely necessary.
• Ceftriaxone can cross the placenta, so don't use it when you don't have to in late pregnancy.
• There isn't a lot of information about sulbactam, however there isn't a recognized major risk.
• Must be provided under the close supervision of a doctor or gynecologist.
• Safe during labor, although moms who bleed easily should be careful.

Faq For Medicine

Q 1. What is the purpose of Xone SB Injection?

It cures moderate to severe bacterial infections that need two drugs to work (ceftriaxone and sulbactam).

Q2. Why does it include Sulbactam in it?

Sulbactam stops bacteria from becoming resistant by stopping beta-lactamase enzymes and making ceftriaxone stronger.

Q3. How do you give it?

Only a doctor or nurse can give it to you by an IV (intravenous) or IM (intramuscular) injection.

Q4. Is it safe for kids?

Yes. A lot of babies, kids, and adults utilize Ceftriaxone + Sulbactam. The dose is depending on weight.

Q5. Can women who are breastfeeding take it?

Usually safe. Some of it may get into milk, and babies may rarely get thrush or loose stools.

Q6. How soon does it start to work?

Most patients start to feel better within 24 to 48 hours.

Expert Advice

• Only trained medical practitioners should give it.
• Finish the whole course even if your symptoms get better to stop antibiotic resistance.
• Tell the doctor about
• Kidney or liver problems
• Issues with the gallbladder
• Any history of being allergic to penicillin or cephalosporin
• Don't mix with IV fluids that have calcium in them.
• Drink plenty fluids until you can't.
• Tests on the liver and kidneys and blood counts may be needed for long-term therapy.

 Side Effects

• A lot of the time:
• Pain and edema at the injection site
• Diarrhea
• Feeling sick
• A small rash
• Higher levels of liver enzymes
• Not as common:
• Fever
• Pain in the head
• Dizzy
• Anemia
• Very serious (rare):
• Anaphylaxis (a very bad allergic reaction)
• Severe diarrhea (C. difficile colitis)
• Stones or sludge in the gallbladder
• Kidney problems
• Problems with bleeding
• Get medical help right away if you have a significant response.

 How It Works

• Xone SB Injection has:
• Ceftriaxone (1000 mg)
• An antibiotic of the third generation of cephalosporins
• Stops bacteria from making their cell walls, which kills them.
• Sulbactam (500 mg)
• A substance that stops beta-lactamase
• Stops microorganisms from breaking down ceftriaxone
• Makes antibiotics work against germs that are resistant to them
• Together:
• They work better and more broadly against germs, even those that are resistant.

Medicine Interaction

• Use with care:
• 1. IV solutions that have calcium in them
• Do not mix in the same IV line; there is a chance of precipitation.
• Warfarin and other blood thinners
• Higher chance of bleeding.
• Antibiotics that are aminoglycosides
• (Amikacin, Gentamicin)
• Could make the kidneys more toxic.
• Diuretics that work in loops
• (Furosemide)
• Raises the chance of kidney injury.
• Other types of antibiotics
• Only use under the advice of a doctor.
• Birth control pills
• Long-term use of antibiotics may make them less effective (rare).

 How to Use

• Only a healthcare professional can offer it.
• Ways:
• IV infusion (best)
• IV bolus
• Injection IM
• The dose depends on:
• How old you are and how much you weigh
• How bad the infection is
• Function of the liver and kidneys
• Finish the whole course; don't skip any doses.
• Never mix with calcium solutions in the same IV line.

 Uses / indications

• Xone SB 1000/500 Injection is used for:
• Infections of the lungs
• Pneumonia
• Very bad bronchitis
• Abscess in the lungs
• Infections in the ears, nose, and throat
• Sinusitis
• Tonsillitis
• Infections of the ear
• Infections of the urinary tract
• Complicated and recurring urinary tract infections
• Infections in the stomach
• Typhoid fever
• Peritonitis
• Infections of the biliary tract
• Infections of the skin and soft tissue
• Infections of the Bones and Joints
• Sexually Transmitted Infections
• Gonorrhea
• Infections in the Bloodstream
• Septicemia
• Severe bacterial sepsis
• Infections after surgery