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Telmisartan makes it unsafe to take during pregnancy, especially in the second and third trimesters.

Could hurt the baby's kidneys, lower the amount of amniotic fluid, slow the baby's growth, cause skull problems, or even kill the baby.

Chlorthalidone can cause jaundice in newborns, problems with electrolytes, and less blood flow to the placenta.

Women who want to get pregnant should switch to safer drugs like methyldopa, nifedipine, or labetalol with the help of a doctor.

Q1. What is the purpose of VENPRES-40 AMC?

For treating moderate to severe high blood pressure, especially when one or two drugs don't work.

Q2. Does it make you pee a lot?

Yes, chlorthalidone makes you pee more, especially throughout the day.

Q3. Is it okay to take it once a day?

Yes, it controls blood pressure around the clock with just one dose a day.

Q4. When will BP start to go down?

You might see a difference in 3 to 6 hours, but it will take 2 to 4 weeks for the complete effect.

Q5. Does it make your ankles swell?

Amlodipine may cause swelling, although chlorthalidone may assist in getting rid of extra fluid.

Q6. Is it useful for keeping your blood pressure down over time?

Yes, as long as renal function, electrolytes, and blood pressure are checked routinely.

For optimal results, take the tablet at the same time every day.
Stay away from too much salt, pickles, papad, and packaged foods.
To avoid getting dehydrated, drink enough water.
It is very important to check your blood pressure regularly.
Don't take potassium supplements unless your doctor says to.
Tell your doctor if you have symptoms including swollen ankles, weak muscles, or extreme dizziness.
Don't take too many NSAIDs like ibuprofen or diclofenac.
Don't spend a lot of time in the sun (chlorthalidone may make you more sensitive).

Not as Common:

Very serious (rare):

Telmisartan stops angiotensin II from working, which makes blood vessels relax and lowers blood pressure.
Amlodipine relaxes the muscles in the arteries, which makes them less resistant and lets blood flow better.
Chlorthalidone reduces blood pressure by taking out extra salt and water through the kidneys. This makes the blood volume smaller.
This three-drug treatment lowers blood pressure strongly and for a long time, and it works especially well for resistant hypertension.

Potassium-sparing diuretics like spironolactone and eplerenone can raise potassium levels.
ACE inhibitors and ARBs can cause problems with the kidneys and an imbalance of potassium.
NSAIDs (such as ibuprofen and diclofenac) lower blood pressure and put stress on the kidneys.
Lithium – danger of toxicity
Chlorthalidone, an antidiabetic drug, may have an effect on blood sugar control.
Corticosteroids can lower potassium levels.
Digitalis (Digoxin)—problems with electrolytes make it more hazardous
Alcohol may make you feel more dizzy.
Grapefruit juice boosts the levels of amlodipine.

Take one pill every day with water.
You can take it with or without food.
Don't crush or chew the tablet.
Every day, take it at the same time.
If you forget to take a dose, take it as soon as you can, unless it's close to the following dose.
Don't take twice as much.
Keep checking your blood pressure on a regular basis.