Pregnancy interaction

• Telmisartan (ARB) makes it unsafe to get pregnant, especially in the second and third trimesters.
• Could hurt the baby's kidneys, lower the amount of amniotic fluid, slow growth, or even kill the baby.
• Pregnant women or women who want to get pregnant shouldn't use it.
• Amlodipine alone has a lower risk, but the two together are not safe.
• Methyldopa, labetalol, and nifedipine (if recommended) are safer options.

FAQs for medicine?

Q1. What is the purpose of VENPRES-40 AM?

For treating high blood pressure, especially when taking just one medicine isn't adequate.

Q2: Is it possible to take it once a day?

Yes, it is made to be used once a day.

Q3. Does it make things swell?

Some people may get edema in their ankles and feet after taking amlodipine.

Q4. When will I start to notice results?

BP starts to go down in 3 to 6 hours and reaches its full effect in 2 to 4 weeks.

Q5. Should it be taken in the morning or at night?

Either is OK, but you should take it at the same time every day.

Q6. Is it okay to drink alcohol with it?

Alcohol might make you feel more dizzy and reduce your blood pressure.

 Expert advice

• Take it every day at the same time.
• Stay away from foods high in salt and potassium replacements.
• Drink plenty of water to keep your blood pressure from dropping suddenly.
• You need to check your blood pressure often.
• Tell your doctor if your ankles are swelling, you're dizzy, or you have a headache that won't go away.
• Don't take NSAIDs like ibuprofen or diclofenac unless a doctor tells you to.
• Even if your blood pressure seems to be under control, don't quit suddenly.

Side Effects

Common:

• Feeling dizzy
• Swelling in the ankle (because of Amlodipine)
• Pain in the head
• Tiredness
• Flushing
• Heart palpitations
• Discomfort in the stomach

Not so common:

• Cramps in the muscles
• High amount of potassium
• Blood pressure is low
• Feeling sick

Serious (Rare):

• A bad allergic reaction
• Very low blood pressure
• Problems with the kidneys (because of Telmisartan)
• If these happen, see a doctor.

How It Works

• Telmisartan stops angiotensin II from working, which stops blood vessels from tightening. This makes blood vessels relax and lowers blood pressure.
• Amlodipine relaxes the smooth muscles of blood arteries, which makes it easier for blood to flow.
• The combo works better than either medicine alone to regulate blood pressure.
• Helps lower the chances of having a stroke, heart attack, or kidney injury.

Medicine interaction

• Potassium-sparing diuretics (spironolactone, eplerenone)—increased risk of potassium levels rising
• ACE inhibitors and other ARBs raise the risk of renal problems.
• Lithium—danger of toxicity
• NSAIDs (such as diclofenac and ibuprofen) may make the drug less effective and hurt the kidneys.
• Other antihypertensives can make blood pressure decrease too much.
• Diuretics—first, a dramatic drop in blood pressure
• Grapefruit juice may raise the levels of amlodipine.
• Drinking alcohol makes you feel dizzy.

How to use

• Take one pill per day with water.
• You can take it with or without food.
• Every day, take it at the same time.
• Do NOT chew or crush the tablet.
• If you miss a dose, take it quickly unless it's near to the next one.
• Don't take two doses.

Uses/indications

• Blood pressure that is too high (hypertension)
• When BP is not managed with Telmisartan alone
• Patients with high blood pressure who need medication with two different types of drugs
• Lowers the chance of heart attack, stroke, and kidney problems in people who are at high risk.