Uses / Indications:
You should take Pletoz 100mg Tablet for:
Intermittent Claudication is a disorder that makes your legs hurt or cramp when you walk because your blood doesn't flow well (Peripheral Arterial Disease).
Better blood flow means more oxygen and nutrients get to the muscles in your legs.
Reduces Platelet Clumping, which stops tiny blood clots from forming in peripheral arteries.
This prescription doesn't cure artery disease, but it does help you walk farther and feel less tired and leg pain.
Pregnancy interaction:
Not a good idea to do while pregnant.
It is not known if Cilostazol is safe for pregnant women.
Studies on animals show that there may be a risk to the fetus.
Only use if the advantages are greater than the hazards and a doctor says so.
Women who can get pregnant should take adequate birth control while they are being treated.
It is not known if Cilostazol gets into breast milk.
Don't use while breastfeeding unless you have to.
If you are nursing, talk to your doctor about other treatments.
Expert advice:
Don't take it if you have heart failure.
Don't smoke because it makes vascular disease worse.
Take it every day for 2 to 3 months before deciding if it has helped.
Check your blood pressure and let your doctor know if you feel your heart racing or fainting.
If alcohol or caffeine makes your headaches or dizziness worse, stay away from them.
Drink plenty of water and eat a balanced diet to help your blood flow.
If you have peripheral artery disease, make sure you wear the right shoes and take care of your feet.
Side Effects:
Dizziness or headache
Upset stomach or diarrhea
Feeling sick or throwing up
Palpitations (a rapid heartbeat)
Feet or ankles that are swollen
Pain in the stomach
Serious (Get medical help right away):
Pain in the chest or trouble breathing
Heart that beats too fast
Severe headache or passing out
Bleeding or bruising that isn't normal
Signs of heart failure include gaining weight, swelling, and trouble breathing.
⚠️ Important: Cilostazol should not be given to people with heart failure since it can make the condition worse.
How to use:
Take one tablet (100 mg) twice a day or as directed by your doctor.
For optimum absorption, take it 30 minutes before or 2 hours after eating.
Do not crumble or chew; just swallow whole with water.
Stick to a regular schedule, with the same time every day.
Don't quit suddenly unless your doctor tells you to.
If there is no improvement after three months, see your doctor again for a checkup.
How it works:
Cilostazol is a drug that blocks phosphodiesterase-III (PDE3).
It raises the level of cyclic AMP (cAMP) in platelets and blood vessels, which leads to:
Vasodilation is when blood vessels relax and blood flow gets better.
Antiplatelet action means that it stops blood platelets from adhering together and making clots.
This dual action helps persons with circulation difficulties feel better by relieving discomfort and cramping and making it easier for them to walk.
Faq for medicine:
What is Pletoz 100mg used for?
A: People with peripheral artery disease use it to get better blood flow and less pain in their legs.
Q2. How long does it take for Pletoz to work?
A: You might see some improvement in 2 to 4 weeks, but the most benefit might not happen for up to 12 weeks.
Q3: Is it safe for me to take Pletoz if I have heart problems?
A: No. If you have or have had heart failure, you shouldn't take it.
Q4. Is it safe to take Pletoz with aspirin or clopidogrel?
A: Yes, but only with a doctor's supervision because the risk of bleeding goes higher.
Q5. What should I not do while taking Pletoz?
A: Don't drink grapefruit juice, alcohol, or over-the-counter blood thinners without first talking to your doctor.
Q6. What if I forget to take my dose?
A: Take it as soon as you recall, unless it's close to your next dose. Don't take twice as much.
Q7. Is it safe to use for a long time?
A: If the advantages outweigh the hazards, it can be used for a long time under a doctor's care
Medicine interaction:
Anticoagulants and antiplatelets (such aspirin, clopidogrel, and warfarin) make bleeding more likely.
Inhibitors of CYP3A4 or CYP2C19 (Erythromycin, Ketoconazole, Omeprazole) raise the levels of Cilostazol in the blood.
Other vasodilators and antihypertensives may make blood pressure too low.
Avoid taking heart failure drugs together because they can be bad for your heart.
Grapefruit juice: May raise the level of Cilostazol in the body; best to stay away from it.
Always let your doctor know about any vitamins or medicines you use.