Permin Cream is an antiparasitic medicine. It is used to treat scabies, a disorder in which microscopic insects infest and irritate the skin. This treatment kills the insects (mites) and their eggs. Scabies is caused by small insects known as mites, which infest and irritate your skin. Permin Cream is an antiparasitic medication. It acts by paralyzing and destroying both mites and their eggs. In general, the cream should be applied all over the body except for the face and head, but see your doctor first. It should be fully rinsed away after 8-12 hours. Often, one treatment is sufficient to treat the problem completely; however, a second application may be required a week later. This will eliminate the itching, swelling, and redness produced by mites. However, deceased mites may still cause you to itch for some time.