Uses / Indications:
Only for serious bacterial infections, especially when safer medications don't work or aren't available:
Typhoid and paratyphoid fever
Meningitis and brain abscess
Infections caused by Rickettsia, such as Rocky Mountain spotted fever
Infections that don't need oxygen
Severe eye infections (also available as drops or ointments for the eyes)
Haemophilus influenzae or Neisseria meningitidis can produce very serious illnesses.
Pregnancy interaction:
Not advised during pregnancy unless there are no other options.
The substance can pass through the placenta and harm the baby.
Using drugs late in pregnancy can create "gray baby syndrome," which is a life-threatening disease in babies because their bodies can't break down the drugs properly.
Only use if the doctor thinks the benefits are greater than the risks.
Expert advice:
Only use this under close medical supervision.
Don't take this drug on your own or give it to anyone else.
Tell your doctor if you have symptoms like unusual bleeding, a sore throat that won't go away, a fever, or excessive exhaustion. These could be signs of a blood disorder.
If treatment lasts a long time, you may need to have your blood count checked regularly.
Don't drink alcohol because it could make adverse effects worse.
Don't ever give it to babies without talking to a doctor first.
Side Effects:
Normal:
Nausea and throwing up
Stomach discomfort and diarrhea
Itching or a rash on the skin
Pain in the head
Important yet rare:
Bone marrow suppression leads to anemia, leukopenia, and thrombocytopenia.
Aplastic anemia (which can be deadly and permanent)
Gray infant syndrome in newborns
Peripheral neuropathy (nerve issues) that last a long time
Reactions to allergens (swelling, rash, trouble breathing)
How to use:
Follow your doctor's instructions exactly.
The usual dose for adults is 500 mg every 6 hours; however, the dose changes depending on the infection.
You can take it with or without food. If your stomach hurts, take it with food.
Do not smash until told to. Swallow whole with water.
Finish the whole course, even if your symptoms become better.
If you forget to take a dose, take it as soon as you remember. If you're close to the following dose, skip it (don't take two doses).
How it works:
Chloramphenicol is an antibiotic that stops bacteria from growing.
It acts by stopping bacteria from making proteins (it binds to the 50S ribosomal subunit).
This stops bacteria from growing and helps keep infections in check.
Faq for medicine:
Q1. Is it safe to take Paraxin 500mg Capsule when pregnant? No, it is not used until it is absolutely necessary.
Q2: Is it safe to take this medication while breastfeeding? No, it gets into breast milk and could be harmful to babies.
Q3. Is it okay to use for the flu or a cold? No, it is an antibiotic, which means it can only kill bacteria, not viruses.
Q4. Are the side effects harmful? Yes, using it for a long time could induce bone marrow suppression or possibly aplastic anemia.
Q5. Why is it not given out as often now?
Medicine interaction:
Warfarin and other blood thinners raise the risk of bleeding.
Changes in medication levels for Phenytoin and Phenobarbital
Sulfonylureas, which are antidiabetic medications, can lead to a risk of low blood sugar.
Chemotherapy, co-trimoxazole, and linezolid are other medications that inhibit bone marrow and make it more hazardous.
Alcohol makes side effects worse.
