Uses / Indications:
The Nicophenicol 250 mg Capsule is used for:
Typhoid fever and paratyphoid fever
Bacterial meningitis
Infections of the respiratory tract (like pneumonia)
Infections in the eyes or ears that are serious
UTIs, or urinary tract infections, are caused by bacteria that can get into the body.
Rickettsial illnesses, including Rocky Mountain spotted fever,
Brain abscess resulting from certain bacterium
Pregnancy interaction:
Chloramphenicol is an antibiotic that is used to treat serious bacterial infections. Nicophenicol 250 mg Capsule includes it.
It should only be used during pregnancy if it is really required, as it may cross the placenta and have an effect on the fetus.
In rare situations, using it late in pregnancy might induce "gray baby syndrome," which is a dangerous disease in babies.
So, unless a doctor says it's okay for life-threatening infections, it should be avoided throughout the last trimester.
Chloramphenicol may get into breast milk, so you shouldn't take it while you're nursing.
Expert advice:
Follow your doctor's instructions exactly when you take this prescription.
Don't take it on your own or for viral diseases like the flu or a cold.
Don't take iron supplements and antacids at the same time; they might make it harder for your body to absorb them.
Let your doctor know if you notice any signs of anemia, weariness, or pale complexion. Chloramphenicol can sometimes induce bone marrow suppression.
You may need to have your blood counted regularly throughout long-term treatment.
Do not drink alcohol while you are getting therapy to avoid negative effects.
Side Effects:
Feeling sick or throwing up
Diarrhea
Pain in the head
Dizzy
Stomach problems
Very bad side effects (get medical help right away):
Bone marrow suppression (unusual bruising or bleeding, tiredness)
Gray baby syndrome in babies (skin that is bluish and hard to breathe)
Allergic responses, such as rashes, itching, and swelling
Elevated liver enzymes
Problems with vision
How to use:
Take Nicophenicol 250 mg exactly as your doctor tells you to.
Take the capsule whole with water, preferably after meals to avoid stomach distress.
Don't chew or shatter the capsule.
Finish the whole course, even if you feel better.
Don't skip doses, because that can make the treatment less effective and resistant.
How it works:
Chloramphenicol, the active ingredient in Nicophenicol 250 mg Capsule, stops bacteria from making proteins.
It attaches to the 50S ribosomal subunit of bacteria and stops the production of important proteins.
This action blocks bacteria from growing and reproducing, which helps the immune system get rid of the infection.
It stops bacteria from growing (bacteriostatic) and can kill bacteria in high doses (bactericidal).
Interactions with other medicines
Nicophenicol may interact with a number of medications:
Stay away from or use with care:
Warfarin raises the risk of bleeding.
Phenytoin and Phenobarbital may raise the levels of these medicines in the blood.
Rifampicin may make Nicophenicol less effective.
Sulfonylureas may make your blood sugar levels too low.
Oral contraceptives may make birth control less effective.
Cyclosporine or Tacrolimus may make the drug more harmful.
Always tell your doctor about any drugs, herbs, or supplements you are taking.
Faq for medicine:
What is the Nicophenicol 250 mg Capsule used for?
It is used to treat bad bacterial illnesses such typhoid fever, meningitis, respiratory tract infections, eye infections, and some urinary tract infections.
Q2: Is it safe to take Nicophenicol when pregnant?
If there is no safer option, it is not suggested during pregnancy, especially in the third trimester.
Q3. Is it safe to do while breastfeeding?
No, it is usually not safe to do while breastfeeding because it could go into breast milk and harm babies.
Q4: Is it okay to take Nicophenicol with other antibiotics?
It depends on the type of infection. Talk to your doctor before taking it with other antibiotics.
Q5. How long should I take the 250 mg Nicophenicol capsule?
Stick to the time your doctor told you to. Even if your symptoms become better, don't stop therapy early because not finishing it can make antibiotics less effective.
Medicine interaction:
Nicophenicol with Iron|Nicophenicol with Methylcobalamin|Nicophenicol with Rifampicin|Nicophenicol with Cyclosporine|Nicophenicol with Fosphenytoin|Nicophenicol with Tacrolimus|Nicophenicol with Primidone|Nicophenicol with Phenobarbitone|Nicophenicol with Phenytoin|Nicophenicol with Paracetamol / Acetaminophen