Uses / Indications 

• Ulcerative Colitis - Causes and keeps remission in mild to moderate instances
• Inflammatory Bowel Disease (IBD) - Aids in managing colon inflammation
• Proctitis / Proctosigmoiditis - Lessens swelling in the sigmoid colon and rectum
• Avoiding a relapse—helps keep chronic colitis from coming back
• Chronic diarrhea with inflammation: lessens how often and how bad it is
• Other inflammatory conditions of the colon, as directed by a gastroenterologist

 How It Works

• Mesalazine (also known as Mesalamine) is a medication that reduces inflammation.
• Works in the colon to minimize edema, irritation, and inflammation.
• Stops the gut lining from making pro-inflammatory substances including prostaglandins and leukotrienes.
• Helps the mucosa in the intestines recover and lessens symptoms including bleeding, diarrhea, and pain.

 How to Use

• Follow your doctor's instructions exactly
• Usually taken once or twice a day, depending on how it is made.
• Do not crush or chew extended-release pills; just swallow them whole with water.
• Take with or after food to keep your stomach from getting upset.
• Keep getting treatment even if your symptoms become better to avoid a relapse.

Pregnancy Interaction

• Generally deemed safe during pregnancy when necessary
• Mesalazine has not demonstrated notable teratogenic consequences.
• Only use with a doctor's supervision
• Keep an eye on both the mother and the fetus during long-term treatment.
• Keeping a disease in remission usually has more benefits than hazards.

 Side Effects

• Mild stomach pain, nausea, or diarrhea
• Pain in the head
• Itching or a mild rash
• Serious or rare side effects:
• Severe allergic response (rash, edema, trouble breathing)
• Kidney issues (rare) may need to be watched.
• Rarely, liver enzymes go up.
• Blood disorders (rare) - if you are tired or bruised for no reason, see a doctor.
• If you have severe stomach discomfort, bloody diarrhea, jaundice, or an allergic response, you should see a doctor right once.

Medicine Interaction

• Mesalazine might have an effect on:
• Azathioprine / 6-Mercaptopurine – may raise the risk of bone marrow suppression
• Other NSAIDs may make stomach problems worse.
• Antacids with aluminum or magnesium may lower absorption, depending on how they are made.
• Blood thinners (warfarin) - keep an eye on your INR levels
• Tell your doctor about all the vitamins and drugs you use.

Expert Advice

• For optimal effects, take it every day.
• Drink enough water throughout therapy.
• Check the function of the kidneys and liver on a regular basis during long-term therapy.
• Let your doctor know right away if you have new or worse symptoms.
• Follow a diet that is good for inflammatory bowel disease.

Faq For Medicine

Q1. Is it safe for me to take Mesalazine while pregnant?
Yes, it is usually safe, but you should always do it under the care of a doctor.

Q2: How long will it take for me to feel better?
Most of the time, symptoms get better in a few weeks, but full remission may take longer.

Q3. Can I discontinue when the symptoms become better?
No, stopping suddenly could make things worse. Keep going as directed.

Q4. Does it make you gain weight?
No, Mesalazine does not make you gain weight.

Q5. Is it okay to take it with food?
Yes, you can take it with or after food to help your stomach feel better.