Pregnancy Interaction

MEGABURN-60 TABLET is not advised for use during pregnancy. Clinical data regarding the use of MEGABURN-60 TABLETS in expectant women are scarce, and weight-loss treatment provides no medical advantage during pregnancy. Unintentional decrease in the assimilation of vital nutrients may impact fetal development. If pregnancy occurs during the use of MEGABURN-60 TABLET, cease its use immediately and seek medical advice from your healthcare provider. Breastfeeding women should also refrain from its use, as it may diminish the assimilation of essential fat-soluble vitamins necessary for the infant's health.

FAQs for medicine?

Q1. What is the purpose of the MEGABURN-60 TABLET?

It is employed to facilitate weight reduction in overweight adults by inhibiting the absorption of dietary fats.

Q2. What is the typical duration for MEGABURN-60 TABLET to become effective?

Noticeable results typically manifest within 2 to 3 months when accompanied by a low-calorie, low-fat diet and consistent physical activity.

Q3. Is it permissible to take MEGABURN-60 TABLET concurrently with multivitamins?

Yes, but it is recommended to take multivitamins at least two hours before or after orlistat to ensure adequate absorption of vitamins A, D, E, and K.

Q4. Is the MEGABURN-60 TABLET considered secure for extended use?

It may be used safely for a period of six to twelve months when administered under medical supervision. Extended use may necessitate the monitoring of fat-soluble vitamin levels.

Q5. Is it permissible to consume alcohol while using MEGABURN-60 TABLETS?

Occasional consumption of alcohol is not contraindicated; however, intake should be limited, as it contributes additional calories and may diminish the efficacy of weight loss.

Expert advice

• Always administer the MEGABURN-60 TABLET either with or within one hour of a primary meal that contains fat.
• Omit the dose if your meal contains no fat or has been ignored.
• Adhere to a dietary regimen in which no more than 30% of caloric intake is derived from fat.
• Supplement with a multivitamin containing A, D, E, K, and β-carotene to prevent deficiencies.
• Consistent physical activity improves outcomes.
• Cease use immediately if you experience severe abdominal pain or persistent diarrhea.
• Not advisable for pregnant women, lactating mothers, or individuals under 18 years of age.

Side Effects

• Oily or greasy stools
• Elevated gastrointestinal activity or a sense of urgency
• Gas and associated discharge
• Abdominal pain or cramping
• Slight discomfort

Uncommon adverse effects:

• Deficiency of fat-soluble vitamins
• Liver impairment (extremely rare)
• Hypersensitivity reactions (such as erythema and pruritus)
• These effects primarily result from the excretion of unabsorbed lipids through the stool.

How it works

• MEGABURN-60 TABLET functions locally within the gastrointestinal tract by inhibiting pancreatic and gastric lipases, the enzymes responsible for the hydrolysis of dietary fat.
• When these enzymes are inhibited, approximately 25–30% of dietary fat remains unabsorbed.
• This unabsorbed fat traverses the intestine without damage and is subsequently expelled in the stool.
• Consequently, caloric consumption diminishes, facilitating a progressive and consistent loss of weight.
• Given that the MEGABURN-60 TABLET functions locally with minimal systemic absorption, systemic adverse effects are infrequently observed.

Medicine Interaction

• Warfarin and other anticoagulants may affect blood coagulation by impairing vitamin K absorption.
• Levothyroxine—may necessitate dose modification; administer orlistat and levothyroxine with a four-hour interval.
• Cyclosporine—absorption is diminished; administer with a minimum interval of 3 hours.
• Fat-soluble vitamins or supplements should be taken either two hours prior to or two hours following orlistat administration.
• Always notify your physician of all medications and supplements you are currently using.

How to Use

• Dosage: One capsule of Orlistat 60 mg taken three times daily with each primary meal containing fat.
• Administration: Swallow with water during or within one hour following the meal.
• omitted dose: Omit it if the meal was omitted or lacked fat.
• Adhere to a balanced, low-calorie dietary regimen coupled with a consistent exercise routine.
• Do not surpass the recommended dosage.

Uses/Indications

• Management of Obesity and Overweight
• Weight loss in individuals with a BMI of 25 kg/m² or higher
• Strategies for preventing weight restoration following initial weight loss
• Complementary treatment alongside a calorie-restricted diet and regular physical activity