One antifungal drug is Leezole Gel. By breaking down the fungal cell membrane, it destroys the fungus and prevents it from growing.Fungal vaginal infections are treated with leezole gel. One antifungal medication is Leezole Gel. It is used to treat fungal infections in adults. It relieves your symptoms and eradicates the infection by preventing the growth of fungus. This medication lessens discharge and relieves discomfort and itching. Even if the symptoms have subsided, keep taking the medication as directed. This will prevent the infection from coming back. by treating your infection.