Uses / Indications:
Prevention and long-term management of angina pectoris (chest pain due to coronary artery disease).
Sometimes used off-label for heart failure (as part of combination therapy).
Pregnancy interaction:
Safety:Ismo 10mg Tablet is generally not recommended during pregnancy unless clearly needed.
Reason: Limited data is available on its safety in pregnant women. It may reduce placental blood flow due to its vasodilatory effects.
Advice: Use only if prescribed by a doctor after carefully weighing risks and benefits.
Expert advice:
Take the tablet at the same time daily for maximum effect.
Do not crush or chew; swallow whole with water.
This medicine is not for immediate relief of chest pain; it prevents angina but does not stop acute attacks.
Do not stop abruptly without consulting your doctor.
Rise slowly from sitting or lying position to avoid dizziness.
Keep a nitrate-free interval (usually nighttime) as advised to prevent tolerance (reduced effect).
Side Effects:
Common side effects:
Headache (most common, usually improves after few days)
Dizziness or lightheadedness
Low blood pressure
Flushing (warmth, redness, or tingling)
Nausea
Serious (rare) side effects:
Fainting
Fast or irregular heartbeat
Severe hypotension
Seek immediate medical attention if chest pain worsens or does not improve.
How to use:
Take orally with water, with or without food.
Follow the dosing schedule strictly as prescribed.
Do not crush or chew extended-release tablets.
If you miss a dose, take it as soon as you remember; if it’s almost time for next dose, skip the missed dose.
How it works:
Ismo 10mg Tablet is a nitrate that relaxes and widens blood vessels.
It works by releasing nitric oxide, which increases cyclic GMP in smooth muscles.
This reduces preload and afterload on the heart, lowering oxygen demand and preventing angina attacks.
Faq for medicine:
FAQs for Ismo 10mg Tablet
Q1. What is Ismo 10mg Tablet used for?
It is used to prevent and treat angina pectoris (chest pain due to heart disease).
Q2. Can I take it during pregnancy?
Only if prescribed by your doctor. It is not routinely recommended.
Q3. Will it cure angina permanently?
No, it helps in preventing angina attacks but does not cure heart disease.
Q4. Can I stop the medicine suddenly?
No, stopping suddenly may worsen angina. Consult your doctor before discontinuing.
Q5. Can I drink alcohol with this medicine?
Avoid alcohol, as it can increase dizziness, low blood pressure, and fainting risk.
Medicine interaction:
Avoid using with:
Phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil, vardenafil) → severe drop in blood pressure.
Other nitrates or nitroglycerin → additive effects.
Alcohol → increased dizziness, fainting risk.
Antihypertensives, beta-blockers, calcium channel blockers → may enhance blood pressure-lowering effects.