Pregnancy interaction

• Clobetasol is a very strong steroid that should not be used during pregnancy unless absolutely essential.
• Neomycin can get into the body through broken skin, and using it for a long time can make your ears hurt.
• Topical ketoconazole has little systemic absorption, although its safety during pregnancy is not entirely confirmed.
• Clioquinol (iodochlorhydroxyquinoline) might be absorbed; hence, it is not safe to take while pregnant.
• There isn't a lot of information about tolnaftate during pregnancy, although it is thought to be low-risk.
• Overall: Only use if your doctor tells you to, and don't use it over huge regions, for a long time, or beneath tight clothing.

FAQs for Medicine?
 

Q1. What is this mix used for?
For treating skin infections that are caused by a mix of fungi, bacteria, and inflammation.

Q2. Is this cream a type of steroid?
Yes. It has clobetasol in it, which is a really potent steroid that you put on your skin.

Q3: Is it okay to put this cream on my face?
Don't use it on your face unless your doctor says it's okay. It could make your skin thinner, cause acne, or change the color of your skin.

4. Is this cream enough to treat a fungal infection?
It can get rid of fungal infections, but it has a strong steroid in it; therefore, you should only use antifungal creams on minor fungal infections.

Q5. How long do I need to use this?
Most of the time, only 5 to 7 days. Long-term use can have serious adverse effects.

Q6. Is it safe for kids?
It is not safe for youngsters to use high-potency steroids like clobetasol unless they are well watched.

Q7: Can I put it on my private parts?
Don't use unless your doctor says to; steroids might hurt sensitive skin.

Q8. Is it okay to put a bandage over the area that was treated?
No. It makes side effects worse and makes absorption better.

 

Expert advice

• Only put on a thin layer; don't massage it in hard.
• Do not use to treat acne, dark spots, itching, or fairness.
• Stop using if your symptoms get worse. Steroids might hide a fungal infection.
• To avoid thinning skin, stretch marks, and hormonal changes, don't use it for a long time.
• Not good for broken skin, big expanses of skin, or long periods of time.
• Avoid getting it in your eyes, mouth, or open wounds.
• Don't use it with other steroid creams or items that irritate the skin.

Side Effects

• Feeling like you're burning or stinging
• Redness or irritation
• Dryness
• Itching
• Skin peeling
• Not as Common
• Thinning of the skin (atrophy)
• Striae, or stretch marks
• Breakouts that look like acne
• Too much hair growth on the area where it was applied
• Skin getting darker or lighter
• Higher chance of getting secondary infections
• Serious (long-term/high absorption)
• Hormonal impacts (not very common)
• Wound healing that takes longer
• Ototoxicity from long-term exposure to Neomycin (rare)

How It Works

Clobetasol (steroid)

• Very strong anti-inflammatory agent
• Decreases redness, swelling, and itching

Neomycin (an antibiotic)

• It kills a lot of Gram-negative bacteria.
• Stops or cures bacterial superinfection

Ketoconazole (for fungal infections)

• Stops the production of ergosterol, which is important for the membranes of fungal cells.
• Works against dermatophytes and yeasts, such as Candida.

 Iodochlorhydroxyquinoline (Clioquinol)

• Has the ability to kill fungi, germs, and parasites
• Helpful for infections that are mixed or fungal instances that don't respond to treatment

Tolnaftate (for fungal infections)

• Stops fungi from growing
• Works well for infections caused by dermatophytes, such as athlete's foot and ringworm.
• The combination works by preventing fungal development (ketoconazole + tolnaftate + clioquinol), killing bacteria (neomycin), and lowering inflammation (steroid).

Medicine interaction

• Other steroids that are used on the skin
• Other antifungal and antibiotic creams (risk of irritation)
• Benzoyl peroxide and retinoids (tretinoin)
• Soaps, scrubs, or chemical peels with medicine in them
• Immunosuppressants
• High doses of aminoglycoside antibiotics (uncommon cumulative toxicity)

Medicines for the inside:

• There aren't any big interactions, but you should always tell your doctor if you're taking blood thinners, antibiotics, antifungals, or systemic steroids.

How to Use

• Make sure the area is clean and dry.
• Put on a thin coating once or twice a day, or as directed.
• Don't put a bandage on it.
• Don't touch your eyes, nose, or mouth.
• Only use for a short time to avoid problems with steroids.
• Don't use it again until your doctor tells you to.
• For kids, only under a doctor's supervision.

Uses/indications

• This mix is used to treat:
• Skin infections caused by both fungi and bacteria
• Dermatitis that is infected
• Eczema that is infected
• Dermatitis caused by an allergy or irritation, with a subsequent infection
• Ringworm with swelling
• Athlete's foot, jock itch (only if infected and steroids are needed)
• Intertrigo (under breast/groin) with infection
• Tinea corporis, Tinea cruris, Tinea pedis (only with a doctor's permission)