Clofresh-V Vaginal Gel is an antifungal medicine. It treats fungal vaginal infections, which can cause burning, itching, and abnormal discharge. Clofresh-V Vaginal Gel is an antifungal medication. It is used to treat fungal infections in adults. It works by inhibiting the growth of fungus, hence relieving symptoms and eliminating the illness. This medication relieves pain, irritation, and decreases discharge. Even if your symptoms have subsided, continue to take the medication for the duration advised. This will prevent the infection from returning.