Uses / Indications:
Chronic heart failure (lower ejection fraction)
In heart failure patients, it improves survival and lowers the need for hospitalization.
Improves how the heart works and keeps symptoms like shortness of breath and tiredness in check.
Pregnancy interaction:
Azmarda 100mg Tablet is made up of Sacubitril (49mg) and Valsartan (51mg). It is mostly used to treat chronic heart failure.
Pregnancy: ❌ Not safe to use while pregnant.
Azmarda can hurt the unborn fetus very badly, even killing it, especially if it is taken in the second or third trimester. This medicine should not be taken by women who are pregnant or wanting to get pregnant. If you get pregnant while taking the prescription, you should stop taking it right away and see a doctor.
Not suggested for breastfeeding because both parts could go into the milk and hurt the baby.
Contraception: Women who could get pregnant should use effective birth control while they are taking the medicine and for at least a week after they stop taking it.
Expert advice:
If you are pregnant, trying to get pregnant, or breastfeeding, don't use Azmarda.
Check your potassium levels, blood pressure, and kidney function on a regular basis.
Do not use ACE inhibitors (such Enalapril or Ramipril) within 36 hours of or after taking Azmarda.
If your face, lips, or tongue swell up (angioedema), tell your doctor right away.
Don't use salt alternatives that have potassium in them, because Azmarda can raise potassium levels.
Don't stop taking the medicine all of a sudden without talking to your doctor beforehand.
Side Effects:
Low blood pressure (hypotension)
Feeling dizzy or passing out
More potassium in the blood (hyperkalemia)
Cough
Tiredness
Changes in how the kidneys work
Serious side effects:
Angioedema is when the cheeks, lips, tongue, or throat swell.
Very low blood pressure
High potassium causing an erratic heartbeat
Kidney function getting worse
If you have trouble breathing, severe dizziness, or swelling, you should see a doctor right once.
How to use:
You can take the tablet with or without food and drink it with water.
The usual starting dose is 50 mg twice a day, which your doctor will tell you to slowly raise to 100 mg twice a day.
For optimal effects, take it at the same times every day.
Don't chew or crush the tablet.
If you forget to take a dose, do it as soon as you recall. If it's almost time for the next dose, skip the one you missed. Don't take two doses.
Keep it in a cool, dry spot where it won't get wet or get too much sun.
How it works:
Sacubitril is a neprilysin inhibitor, which means it raises levels of good peptides that relax blood vessels, help the body get rid of sodium, and lessen the strain on the heart.
Valsartan is an angiotensin II receptor blocker (ARB) that stops blood vessels from getting smaller. This helps lower blood pressure and stress on the heart.
Together, they make the heart work better, lower the number of hospitalizations, and help people with heart failure live longer.
Faq for medicine:
1. What is the Azmarda 100mg Tablet for?
It is used to treat chronic heart failure (reduced ejection fraction) to lower the chance of hospitalization and death from heart-related causes.
Q2: Is it safe to take Azmarda when pregnant?
No. It is absolutely forbidden in pregnancy due to the potential of fetal damage.
Q3. Is Azmarda a drug for high blood pressure?
Azmarda is not primarily used for hypertension; it is used to treat heart failure and lower blood pressure.
Q4. Can you eat Azmarda?
Yes. You can take it with or without food, but you should take it at the same time every day.
Q5: How long does it take for Azmarda to work?
You can find that your heart works better and your symptoms become better after a few weeks to months of using it regularly.
Medicine interaction:
ACE inhibitors (Enalapril, Ramipril) can cause angioedema, thus wait at least 36 hours between doses.
Aliskiren (particularly in people with diabetes) can harm the kidneys and raise potassium levels.
Potassium supplements or salt substitutes may induce too much potassium in the blood.
NSAIDs (such ibuprofen and diclofenac) can make renal function worse.
Lithium—raises the chance of lithium poisoning.
Other blood pressure drugs may make your blood pressure drop too much.
Before you start taking Azmarda, you should always tell your doctor about all the other drugs and supplements you are taking.
