Pregnancy Interaction

• Be careful when using it during pregnancy.
• People usually think that amlodipine is minimal risk, but it should only be used if it is really essential.
• There isn't much evidence that the fetus is harmed, but there isn't much data, therefore safer options are better in early pregnancy.
• It's safe to use in modest amounts while breastfeeding, but talk to your doctor first.

Faq For Medicine

Q1. What does Amlosafe 5 mg do?
For high blood pressure (hypertension) and angina (chest pain associated to the heart).

Q2. Does it make things swell?
Yes. Amlodipine can make your feet or ankles swell (this is the most common side effect).

Q3. When does it start to work?
It takes 4–6 hours for the blood pressure to go down, and 1–2 weeks for it to be fully effective.

Q4. Is it okay to take it at night?
Yes. You can take it in the morning or at night, but you should do it at the same time every day.

Q5. Is it okay to stop taking the medication all of a sudden?
No. Stopping suddenly could cause high blood pressure to come back.

Q6. Is it safe for people with kidney problems?
Yes, it's safe for most people with kidney problems.

Q7. Is it okay to drink alcohol while taking Amlosafe?
Stay away from alcohol because it can make you feel more dizzy and reduce your blood pressure.

Expert Advice

• Take it every day; missing doses makes it harder to control blood pressure.
• To bring down swelling, either raise your legs or eat less salt.
• Don't drink grapefruit juice because it could raise the levels of amlodipine.
• Check your blood pressure often for the first few weeks.
• Keep making improvements to your lifestyle:
• – eat less salt – exercise regularly – don't smoke or become stressed
• Tell your doctor if the swelling gets worse or doesn't go away.

 Side Effects

• Legs and feet swelling
• Feeling dizzy
• Pain in the head
• Flushing (feeling warm)
• Tiredness
• Heart palpitations
• Not as Common:
• Feeling sick
• Pain in the stomach
• Cramps in the muscles
• Sleep problems
• Very serious (rare):
• Very bad allergic reaction
• Very low blood pressure
• A heart that beats too fast or too slowly
• Chest pain that gets worse (rare at first)
• If you get severe dizziness, chest discomfort, or trouble breathing, get medical care right once.

How it works

• Amlodipine (CCB) is a calcium channel blocker.
• Stops calcium from getting into the muscles of blood vessels.
• Makes blood vessels relax and get bigger.
• Lowers blood pressure and makes the heart work less hard.
• Keeps angina from happening by improving blood flow to the heart muscles.
• Overall effect: ✔ Lower blood pressure ✔ Less chest pain ✔ Better blood flow

Medicine Interaction

• Be careful when using with:
• ➤ Other drugs that reduce blood pressure
• Could induce too low of blood pressure.
• ➤ Heart medications or beta-blockers
• In rare situations, it may make a sluggish heart rate or heart block worse.
• ➤ Antifungals (like Itraconazole and Ketoconazole)
• Raise the levels of amlodipine.
• ➤ Antibiotics (Clarithromycin)
• Could boost amlodipine levels, which could cause greater negative effects.
• ➤ Juice from grapefruit
• Avoid because it raises drug levels.
• ➤ Alcohol
• Makes dizziness and low blood pressure worse.

 How to Use

• Take as directed once a day.
• You can take it with or without food.
• Every day, at the same time, take it.
• Take the pill with water.
• If you forget a dose, do the following: – Take it right away if you remember; – Skip it if the next dose is coming up soon; – Do NOT take two doses.

Uses / Indications

• High blood pressure (hypertension)
• Angina (stable chronic angina)
• Prinzmetal's angina, also known as vasospastic angina
• Controlling blood pressure in people who are susceptible to other blood pressure medications
• As a single treatment or as part of a combination treatment for long-term blood pressure control