Uses / Indications:
Treatment of tuberculosis (TB), particularly in patients who are resistant or intolerant to alternative medications.
Sometimes used for serious bacterial infections caused by gram-negative bacteria when safer options aren't accessible.
Pregnancy interaction:
Streptomycin is not advised during pregnancy.
It can go through the placenta and impair the baby's hearing.
Use is only recommended when there is no safer option and the possible benefit is greater than the hazards.
Before using, ladies who are pregnant should talk to their doctor.
Expert advice:
A trained healthcare provider must give this drug.
While you are being treated, you need to check your kidney function and hearing on a regular basis.
Unless told otherwise, drink a lot of fluids.
To stop drug resistance, you need to finish the whole course of therapy.
Tell your doctor if you have kidney illness, trouble hearing, or are pregnant or nursing.
Tell your doctor right away if you have symptoms like ringing in your ears, dizziness, losing your balance, or peeing less.
Side Effects:
Side effects that happen often:
Pain at the site of the injection
Nausea and throwing up
Feeling dizzy
Pain in the head
Serious side effects that need medical attention:
Hearing loss, ringing in the ears, and balance problems are all signs of ototoxicity.
Nephrotoxicity (less urine output, injury to the kidneys)
Allergic reactions include rashes, itching, swelling, and trouble breathing.
Neuromuscular blockage (rare, hard to move or breathe)
How to use:
Only given by injection into the muscle.
The dose depends on how old you are, how much you weigh, how well your kidneys work, and how bad the illness is.
Not to be self-administered.
Along with additional anti-TB medications, treatment is frequently administered
How it works:
Streptomycin, also known as Ambistryn-S, is an aminoglycoside antibiotic.
It kills bacteria by stopping them from making proteins.
It works very well against the microorganisms that cause TB, Mycobacterium tuberculosis.
Faq for medicine:
Q1: What is the purpose of Ambistryn-S Injection?
It is used to treat tuberculosis (TB), usually together with other anti-TB drugs.
Q2. Is it safe to have this shot when I'm pregnant?
No, it is usually not safe to do during pregnancy, unless the doctor thinks the advantages outweigh the dangers in a life-threatening circumstance.
Q3. Will this medicine make you want to take it again?
No, it doesn't make you addicted.
Q4. What is the method of giving this injection?
A healthcare professional gives it as an intramuscular (IM) injection.
Q5. Does Ambistryn-S hurt your kidneys?
Yes, Streptomycin can be hazardous to the kidneys in some people, so their renal function needs to be checked.
Q6. Is it okay to nurse while taking Ambistryn-S?
Streptomycin gets into breast milk. While breastfeeding, you need be careful with it.
Medicine interaction:
Ambistryn-S may have effects on:
Other aminoglycosides (gentamicin, amikacin) → ↑ risk of harm to the kidneys and ears.
Vancomycin and amphotericin B make the kidneys more toxic.
Diuretics (furosemide, ethacrynic acid) increase the risk of ototoxicity.
Muscle relaxants and anesthetics may make the risk of neuromuscular blockade higher
