Uses / Indications:
Not enough vitamin D
Osteoporosis (bones that are weak or brittle)
Osteomalacia and rickets are conditions that cause bones to become soft.
Hypoparathyroidism (low calcium and low parathyroid hormone)
Chronic kidney illness (renal osteodystrophy)
Problems with calcium and phosphate metabolism
Pregnancy interaction:
Adova (Alfacalcidol) should only be used during pregnancy if absolutely necessary.
Too much vitamin D can raise calcium levels (hypercalcemia), which could hurt the infant.
Pregnant women should only use it with close medical supervision and regular checks of their calcium and vitamin D levels.
Expert advice:
Do not take more than the specified dose; take it exactly as directed.
Drink enough water to lower your risk of getting kidney stones.
Don't take extra vitamin D or calcium supplements unless your doctor tells you to.
You need to get blood tests done on a regular basis to check your calcium and phosphate levels.
Tell your doctor if you have high calcium symptoms including nausea, vomiting, constipation, disorientation, or needing to pee a lot.
Side Effects:
Throwing up and feeling sick
Diarrhea or constipation
Headache and dizziness
Metallic taste in the mouth
Serious (not often):
Hypercalcemia (too much calcium in the blood) can cause tiredness, kidney stones, and stomach pain.
Hyperphosphatemia (high levels of phosphate)
Reactions to allergies (rash, itching, and swelling)
How to use:
Take once a day or as your doctor tells you to.
Do not crumble or chew; just swallow whole with water.
You can take it with or without food.
If you forget to take a dose, take it as soon as you can, unless it's almost time for the next one. Don't take two doses.
How it works:
The liver turns alfacalcidol into calcitriol, which is active vitamin D3.
Calcitriol helps the body absorb more calcium and phosphate from the intestines, controls how bones are made, and makes parathyroid hormone work better.
This helps keep bones strong, stop rickets and osteomalacia, and fix calcium insufficiency.
Faq for medicine:
Q1. Is it safe to take Adova when pregnant?
Only if a doctor says so. High amounts could hurt the baby.
Q2. Is it safe to use when nursing?
Be careful when using. It can get into breast milk and change the baby's calcium levels.
Q3: Is it okay to take calcium supplements with Adova?
Yes, but only if your doctor says it's okay. Taking both without checking may raise calcium levels.
Q4. How long does it take to work?
It may take a few weeks for vitamin D and calcium levels to get better, but it takes longer for bone health to get better.
Q5. Do I need to be tested often while I'm taking it?
Yes, you should keep an eye on your calcium, phosphate, kidney function, and vitamin D levels on a regular basis.
Medicine interaction:
Taking other vitamin D or calcium supplements can raise the risk of hypercalcemia.
Thiazide diuretics (hydrochlorothiazide) -> Could raise calcium levels
Digitalis (digoxin) → If calcium levels go up, the risk of cardiac rhythm disorders goes up.
Anticonvulsants (phenytoin, phenobarbital) -> May lessen the impact of vitamin D
Corticosteroids → May negate the advantages of vitamin D